Lipid regulator linked to good breast milk
Lipid regulator linked to good breast milk LA JOLLA, Calif., Aug. 15 (UPI) -- U.S. scientists have discovered a nuclear receptor that regulates fat storage is a vital link in the production of high quality breast milk.
Researchers at the Salk Institute for Biological Studies determined mouse mammary glands deficient in the regulator PPARa produce toxic milk that causes inflammation and baldness in suckling pups.
"We were quite surprised by the unexpected quality control mechanism that ensures the quality of breast milk," said Professor Ronald Evans, who led the study. "Our finding explains why breast milk is always clean and healthful, even when there’s a lot of inflammation going on in the mother’s body."
Evans and colleagues hope a better understanding of PPARa will lead to understanding the role lipids and inflammation play in hair loss and other skin disorders.
The research appears in the August issue of the journal Genes & Development.
Quoted from http://www.upi.com/NewsTrack/Science/2007/08/15/lipid_regulator_linked_to_good_breast_milk/2729/:
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